Jesus Luzardo allowed just two hits over seven innings as the Philadelphia Phillies topped the visiting San Francisco Giants 7-0 on Tuesday, hours after firing manager Rob Thomson.

With a 9-19 record entering Tuesday that was tied for the worst mark in the major leagues, the Phillies opted to part ways with Thomson, who had managed the squad for nearly four years. Bench coach Don Mattingly was promoted to interim skipper and enjoyed a victorious debut thanks to Luzardo's gem and a four-run sixth from the Philadelphia offense.

Trea Turner went 4-for-5 with two runs for the Phillies, while Adolis Garcia drove in two runs. Luzardo (2-3) took care of the rest, striking out eight without a walk to help Philadelphia win for just the second time in its past 13 games.

San Francisco starter Tyler Mahle (1-4) allowed five runs and six hits in five-plus innings. Matt Chapman accounted for four of the 12 strikeouts by the Giants, who had won seven of their previous 10 games.

Marlins 2, Dodgers 1

Janson Junk (2-2) pitched six scoreless innings, Otto Lopez had three hits and visiting Miami held on to beat Los Angeles.

Owen Caissie and Kyle Stowers each drove in a run as the Marlins improved to 2-3 on a six-game West Coast road trip. Tyler Phillips pitched a scoreless ninth inning for his second save after closer Pete Fairbanks went on the injured list earlier in the day.

Dodgers starter Shohei Ohtani (2-1) gave up two runs (one earned) on five hits over six innings. Will Smith had three of Los Angeles' seven hits.

Blue Jays 3, Red Sox 0

Trey Yesavage pitched 5 1/3 sharp innings in his season debut and Toronto shut out visiting Boston to even a three-game series.

Yesavage (1-0) allowed just four hits. Vladimir Guerrero Jr. had two hits and an RBI while Kazuma Okamoto had a two-run single to help the Blue Jays end Boston's three-game winning streak. Louis Varland struck out the side in the ninth to earn his fourth save.

Boston starter Payton Tolle (0-1) allowed three runs on three hits in 4 2/3 innings.

Rays 1, Guardians 0

Jonathan Aranda had an RBI single in the fifth inning and Nick Martinez and three relievers combined on a four-hitter as the visiting Tampa Bay edged Cleveland.

Martinez (2-1) worked seven-plus innings, lowering his ERA to 1.70. Cole Sulser tossed the ninth for his first save since 2022 with the Miami Marlins. The Rays are a season-best seven games above .500 at 18-11.

The first overall pick in the 2024 draft, Travis Bazzana, made his major league debut for Cleveland, and he went 0-for-2 with two walks. Tanner Bibee (0-4) allowed one run on four hits over five innings.

Yankees 3, Rangers 2

Cam Schlittler pitched six shutout innings to best Jacob deGrom, and Aaron Judge homered for the third straight game as New York hung on for a victory in Arlington, Texas.

The Yankees won for the 10th time in 11 games as Schlittler (4-1) allowed just three hits. Austin Wells added a homer for New York.

deGrom (2-1) gave up a run on three hits in six innings. Danny Jansen (triple) and Josh Jung (single) had RBI hits in the ninth inning before David Bednar got Corey Seager to bounce into a game-ending double play, sealing his ninth save.

Reds 7, Rockies 2

Elly De La Cruz went 3-for-4 and drove in four runs while Spencer Steer belted a two-run homer as Cincinnati beat visiting Colorado.

With his eighth inning two-run shot, De La Cruz now has 10 homers, tied with three others for the most by any switch hitter before May since 1900. Chase Burns (3-1) allowed just two runs in six innings as the Reds won for the eighth time in 10 games.

Edouard Julien went 3-for-4 with a solo home run and drove in both runs for the Rockies, who went 1-for-11 with runners in scoring position and had their three-game win streak snapped. Kyle Freeland (1-2) yielded four runs on five hits over five innings.

Royals 4, Athletics 1 (10 innings)

Bobby Witt Jr. smacked a tiebreaking three-run homer in the top of the 10th inning and Kansas City stretched its winning streak to a season-best four games by beating the Athletics in West Sacramento, Calif.

Salvador Perez also homered for the Royals. Nick Mears (2-1) worked a perfect ninth, and Lucas Erceg escaped a jam in the bottom of the 10th for his seventh save.

Jacob Wilson had an RBI single and Shea Langeliers contributed three hits for the Athletics, who left 14 runners on base. Justin Sterner (1-3) served up Witt's homer.

Orioles 5, Astros 3

Shane Baz earned his first victory with Baltimore and Pete Alonso smacked a two-run homer as the host Orioles handed struggling Houston another loss.

Baz (1-2) held the Astros to one run on six hits in 5 2/3 innings. Alonso connected with two outs in the fifth inning to stretch the lead to 4-1 as the Orioles ended a two-game skid.

Brice Matthews homered among his three hits from the No. 9 spot in the order for the American League-worst Astros. Houston, which is 3-8 across its last 11 games, went 2-for-14 with runners in scoring position.

Braves 5, Tigers 2

Martin Perez pitched five scoreless innings and Ozzie Albies homered to help Atlanta defeat visiting Detroit in the opener of a three-series between division-leading clubs.

Perez (2-1) logged his first win over the Tigers since Aug. 25, 2019. The Braves' nine-hit attack was led by Mike Yastrzemski, who went 2-for-3 with a double and an RBI.

Detroit starter Casey Mize had to leave the game with right groin tightness, and he was charged with two runs in 2 1/3 innings. Wenceel Perez homered for the Tigers in the ninth inning.

Cardinals 11, Pirates 7

Nolan Gorman and Victor Scott II homered and Gorman, Jordan Walker and Alec Burleson each knocked in three runs as visiting St. Louis outslugged Pittsburgh.

The Cardinals scored multiple runs in four different innings, finishing with 12 hits and a season-high run total. Kyle Leahy (3-3) scattered nine hits and allowed three runs in 5 1/3 innings.

Oneil Cruz, Ryan O'Hearn and Konnor Griffin went deep for the Pirates, and O'Hearn knocked in three runs. Braxton Ashcraft (1-2) permitted six runs on six hits in 4 1/3 innings.

Brewers 13, Diamondbacks 2

Sal Frelick went deep to snap Milwaukee's seven-game homerless streak and propel the Brewers to a rout of visiting Arizona. The seven-game streak without a homer was the Brewers' longest since a franchise record 13 games in August 1999.

Milwaukee starter Chad Patrick (2-1) allowed two runs on one hit in five innings. Tyler Black produced three hits and three RBIs, and four other Brewers had two RBIs apiece.

Diamondbacks starter Merrill Kelly (1-2) surrendered five runs on six hits in five innings. James McCann singled in two runs.

Mets 8, Nationals 0

Clay Holmes threw six scoreless innings as New York rolled to a victory over visiting Washington.

Bo Bichette homered leading off the first and Juan Soto's two-run blast closed out a seven-run fourth-inning outburst for the Mets, who are just 3-15 since April 8.

Three players had a hit apiece for the Nationals, who have lost seven of 11. Zack Littell (0-4) yielded eight runs (four earned) in 3 2/3 innings.

White Sox 5, Angels 2

Drew Romo homered from both sides of the plate, Colson Montgomery also went deep and Davis Martin pitched effectively into the sixth inning as the host Chicago defeated Los Angeles.

The White Sox have won the first two games of the three-game series against the Angels, who have lost five in a row and nine of 10. Martin (4-1) allowed one run in 5 2/3 innings. Seranthony Dominguez pitched the ninth inning for his seventh save.

Los Angeles starter Jose Soriano (5-1), who entered with a 0.24 ERA, permitted three runs in five innings. Josh Lowe hit a solo homer.

Mariners 7, Twins 1

Josh Naylor went 3-for-5 with a homer and four RBIs, leading Seattle past Minnesota in Minneapolis.

Julio Rodriguez went 3-for-5 with three doubles and two RBIs for the Mariners, who evened the three-game series at one win apiece. Cole Young finished 3-for-4 with an RBI. Eduard Bazardo (2-1) threw one scoreless inning of relief.

Twins starter Joe Ryan (2-3) gave up two runs on six hits in six-plus innings. Byron Buxton went 2-for-5 with a home run and a stolen base.

Cubs 8, Padres 3

Nico Hoerner's two-run double snapped a sixth-inning tie and Pete Crow-Armstrong broke open the game with a three-run homer in the seventh as visiting Chicago stopped San Diego.

Cubs starter Edward Cabrera (3-0) lasted 5 2/3 innings and allowed three runs on six hits. Dansby Swanson hit a two-run double before exiting the game due to a left glute cramp.

Xander Bogaerts homered for the Padres, who have lost two of three, and Ty France had two hits and an RBI. Kyle Hart (0-1) was charged with two runs in two-thirds of an inning.