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Atlanta Falcons wide receiver Drake London caught 10 of 16 targets for 158 yards and a touchdown in Monday night's 24-14 victory over the Bills. With Darnell Mooney (hamstring) out, London drew a whopping 16 targets on Michael Penix Jr.'s 32 pass attempts. After being held under 60 receiving yards in each of the first three games, London has now recorded back-to-back performances with over 100 receiving yards and a touchdown. London is among the league leaders in targets in a potent Atlanta offense and will be a high-end WR1 again on Sunday night next week against San Francisco.

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Atlanta Falcons running back Bijan Robinson had a career game in Monday night's 24-14 win over the Bills, rushing for 170 yards on 19 carries and catching six of eight targets for 68 yards. The 238 total yards are a career high for the superstar running back as he continues his remarkable season. Atlanta relied solely on Robinson and London to move the ball against Buffalo, with the duo accounting for 396 of the team's 443 total yards. The 23-year-old remains the best running back in fantasy and will be in primetime again next Sunday night against San Francisco.

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The NFL suspended Detroit Lions safety Brian Branch for one game without pay on Monday for his altercation with Kansas City Chiefs wide receiver JuJu Smith-Schuster following Sunday night's game, according to Tom Pelissero of NFL Network. Branch is appealing the suspension. If the league upholds the suspension, Branch will be unavailable to play in the team's Week 7 matchup on Monday Night Football against the Tampa Bay Buccaneers. The Lions' secondary can ill-afford to lose the 23-year-old for a game, although the good news is that the Lions will be facing a banged-up Buccaneers team next week that could be missing all three of their top receivers -- Mike Evans (hamstring), Emeka Egbuka (hamstring), and Chris Godwin (leg) -- due to injuries. Branch was a first-time Pro Bowler in 2024 and remains a big part of Detroit's secondary, logging a sack, 33 total tackles, and a forced fumble through six games in 2025.

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Cincinnati Bengals All-Pro pass-rusher Trey Hendrickson (hip) was estimated as a non-participant on Monday's practice report, according to Jay Morrison of SI.com. Hendrickson was listed with a back injury after leaving Sunday's loss to the Green Bay Packers early, but he's now listed with a hip injury heading into a Week 7 divisional contest on Thursday night against the Pittsburgh Steelers. It's unclear exactly how serious Hendrickson's hip injury is, but with a quick turnaround, it wouldn't be a surprise to see him sit out in Week 7. Either way, he probably isn't going to do much in practice this week. After a league-best 17.5 sacks in 2024, the 30-year-old pass-rusher is up to four sacks in 2025 through six games. The Steelers' offense would catch a big break this week if Hendrickson isn't cleared to play. Fantasy managers in IDP formats need to have a backup plan in place in case Hendrickson is inactive on Thursday evening.

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Buffalo Bills linebacker Terrel Bernard (ankle) is questionable to return to his team's Week 6 matchup against the Atlanta Falcons due to an ankle injury. Bernard recorded two solo tackles before being forced to exit the game. The Bills entered the game without starting linebacker Matt Milano (pectoral), so Bernard's absence leaves them short multiple starters at the position. If Bernard is unable to return in Week 6, Joe Andreessen could finish the game at linebacker for Buffalo.

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Cincinnati Bengals tight end Tanner Hudson (concussion) was listed as a non-participant on the team's Monday injury report due to a concussion. Cincinnati has a short week in Week 7 as they prepare to play the Pittsburgh Steelers on Thursday night, so Hudson appears to be at serious risk of being unavailable. The 30-year-old had not recorded a catch in 2025 heading into Week 6. However, in his first game with new Bengals quarterback Joe Flacco, Hudson recorded four catches for 10 yards and a touchdown on five targets. With fellow Cincinnati tight end Mike Gesicki (pectoral) also questionable to play in Week 7 due to a pectoral injury, Noah Fant could be in line to dominate playing time at the position for the Bengals on Thursday night against Pittsburgh.

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Buffalo Bills wide receiver Joshua Palmer (ankle) has been ruled out for the remainder of his team's Week 6 matchup against the Atlanta Falcons due to an ankle injury. Palmer recorded two catches for 60 yards on two targets before being forced out of the game. With Palmer out, Bills wideouts Keon Coleman and Khalil Shakir could both see an uptick in target share. Additionally, reserve wideouts Tyrell Shavers and Elijah Moore could both see more playing time than usual.

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Indianapolis Colts quarterback Anthony Richardson Sr. (eye) has been placed on Injured Reserve due to an orbital fracture, per ESPN's Stephen Holder. Richardson Sr. suffered the injury in a freak accident while warming up with a stretch band before the Colts' Week 6 matchup with the Arizona Cardinals. The 23-year-old will now miss at least the next four games for Indianapolis, leaving the team without its preferred backup to starting quarterback Daniel Jones. Sixth-round rookie signal-caller Riley Leonard would currently be next in line if Jones were to get injured. However, Holder reports that the Colts will "consider signing a veteran to back up Jones depending on (Richardson Sr.'s) timeline."

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Pittsburgh Steelers wide receiver Calvin Austin III (shoulder) was listed as a non-participant on the team's Monday injury report due to a shoulder injury. Pittsburgh did not actually hold a practice, so this is an estimation of Austin III's status heading into the Steelers' Week 7 matchup against the Cincinnati Bengals on Thursday night. Austin III did not play in Week 6 due to the injury and appears to be at risk of missing a second straight game. The 26-year-old has recorded 10 catches for 139 yards and two touchdowns across four games so far this season. In Austin III's absence in Week 6, Roman Wilson was the only Steelers wide receiver outside of DK Metcalf to record a target.

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Dallas Cowboys Executive Vice President Stephen Jones said that wide receiver KaVontae Turpin (foot) has "a chance" to play in Week 7 against the Washington Commanders, per Jon Machota of The Athletic. Turpin has missed two straight games with a foot injury. The 29-year-old has recorded 11 catches for 159 yards and a touchdown on 13 targets across four games so far this season. Dallas may also be getting star wideout CeeDee Lamb (ankle) back in Week 7, which would likely leave Turpin fighting for WR3 reps in Dallas with Jalen Tolbert and Ryan Flournoy. If Lamb remains out in Week 7, Turpin could have some flex appeal in deep leagues against Washington.

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Buffalo Bills wide receiver Joshua Palmer (ankle) injured his ankle in the first half of Monday night's game against the hosting Atlanta Falcons and is questionable to return, according to ESPN's Alaina Getzenberg. Palmer was taken to the blue medical tent to be evaluated and was seen running up and down the sideline after that to try and get his ankle loose. Buffalo's offense already came into this game short a couple of pass-catchers, with tight end Dalton Kincaid (oblique) and receiver Curtis Samuel (neck, ribs) out. If Palmer is unable to return for the rest of Monday's game, there will be more targets to go around for receivers Khalil Shakir, Keon Coleman, and Elijah Moore, as well as tight end Dawson Knox, who scored the team's first touchdown of the game. At the time of his injury, Palmer was leading the Bills with two catches for 60 yards.

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San Francisco 49ers head coach Kyle Shanahan said on Monday that he thinks wide receiver Brandon Aiyuk (knee) is getting "closer and closer" to being able to return to practice, but there's "no definitive target date for that yet," according to Nick Wagoner of ESPN. Aiyuk is getting closer to practicing after tearing his ACL and MCL in his knee in Week 7 of last year, but his return to actual game action is another story. Once the Niners designate Aiyuk to return from the Physically Unable to Perform list, they'll have 21 days to officially activate him for his 2025 debut. San Fran's receiving corps really has not been healthy all year, but they aren't going to rush Aiyuk back, and fantasy managers still should be expecting his return to come in the second half of the season. Once the former first-rounder is back in the fold, don't be surprised if he's eased back into the offense, given his long layoff.

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San Francisco 49ers head coach Kyle Shanahan said on Monday that wide receiver Ricky Pearsall (knee) will be evaluated on Wednesday with the hope that he can do more in practice this week, according to Nick Wagoner of ESPN. Pearsall suffered a PCL injury to his right knee in Week 4 and has missed the last two games as a result. He was unable to practice at all last week, but he was able to do conditioning work on side fields with trainers. The 25-year-old second-year pass-catcher appears to be making progress, but it's premature to think that he'll be able to return for a Week 7 matchup against the Atlanta Falcons on Sunday. When Pearsall does finally return, tight end George Kittle (hamstring) could be back from Injured Reserve, which would mean fewer targets in the passing game. Fellow wideout Jauan Jennings (ribs) returned in the Week 6 loss to the Tampa Bay Buccaneers, but he revealed he played with five broken ribs.

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Arizona Cardinals head coach Jonathan Gannon cleared things up on Monday for anyone thinking there might be quarterback controversy in the desert after veteran backup Jacoby Brissett's strong performance in the Week 6 loss to the Indianapolis Colts. When asked if Kyler Murray (foot) is still the starter under center when he's healthy, Gannon said, "Yeah." "He's the starting quarterback," Gannon confirmed. Brissett threw for 320 yards, two touchdowns, and an interception on Sunday. The last time that Murray went for over 300 yards passing in a game was in late October of 2022. Although it was just a one-game sample size for Brissett, he looked better than Murray has in his five starts in 2025. The Cardinals organization continues to stand behind Murray as the starting QB, but Brissett's impressive composure in his first start of the year on Sunday could afford the team more patience in bringing Murray back from his foot injury.

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San Francisco 49ers head coach Kyle Shanahan said on Monday that quarterback Brock Purdy (toe) will be evaluated on Wednesday with the hope that he will be able to do more in practice this week, according to Nick Wagoner of ESPN. Purdy aggravated a turf-toe injury in Week 4 and has now missed back-to-back games (four total this year). He did not practice at all last week, but he was seen working on his conditioning on side fields. The 25-year-old signal-caller is believed to be making progress, but his availability for Week 7 against the Atlanta Falcons will all depend on whether he can return to practice this week. There's no question that Purdy is San Fran's starting QB when healthy, but backup Mac Jones' strong play has given the 49ers the luxury of slow-playing Purdy's rehab from his toe injury. We should have a better idea of Purdy's chances of returning this weekend after the Niners hold a few practices later this week.

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Chicago Bears rookie first-round tight end Colston Loveland (hip) is officially active for Monday Night Football against the Washington Commanders to wrap up Week 6 action. Loveland will be returning for the first time since Week 3 due to a hip injury. The 21-year-old sat out of the Week 4 contest and is now ready after having extra time to heal during the team's Week 5 bye. With Loveland back in the fold, quarterback Caleb Williams will have his full complement of targets in the passing game against a suspect Washington secondary. There's a lot to like about Colston's long-term fantasy outlook, but early in his rookie season, he has struggled to produce and will likely take a back seat to Cole Kmet yet again in his return on Monday. In his first three NFL games, Loveland has caught half of his six targets for 43 yards and no touchdowns.

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Washington Commanders running back Chris Rodriguez Jr. (calf) is officially active for the Monday Night Football game against the Chicago Bears in Week 6 despite not practicing all week. Rodriguez, rookie Jacory Croskey-Merritt, and Jeremy McNichols had been operating in a committee backfield after the season-ending injury to Austin Ekeler (Achilles) earlier this year until last week, when Croskey-Merritt took hold of the lead-back role in a breakout performance in the win over the Los Angeles Chargers. It's unclear if Rodriguez will be limited at all on Monday night, but we'd expect him to take a clear back seat to JCM once again against Chicago. The 25-year-old RB should be viewed as a pretty shaky touchdown-dependent RB3/flex in fantasy lineups on Monday. In the last three games, Rodriguez has just over 100 yards rushing and no touchdowns on 23 carries.

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Washington Commanders wide receiver Deebo Samuel Sr. (heel) is officially active for the Monday night contest in Week 6 against the Chicago Bears. Samuel was only able to get in one limited practice going into Monday's game, which is why he was listed as questionable on Saturday's final injury report. However, he'll end up suiting up for Washington, which is good news, considering they will be without both Terry McLaurin (quadriceps) and Noah Brown (groin, knee) for yet another game. It's possible that Samuel won't be entirely 100% health-wise on Monday, but he still deserves to be started in all fantasy lineups now that he's active. Samuel has been the Commanders' go-to offensive weapon through the air in the last two weeks with McLaurin and Brown out, and that shouldn't change much on Monday in a plus matchup. The 29-year-old will be looking to find the end zone for the third straight week.

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In a surprise turn, the Atlanta Falcons have made wide receiver Ray-Ray McCloud III a healthy scratch from the Monday night contest against the visiting Buffalo Bills, according to Tori McElhaney of AtlantaFalcons.com. Darnell Mooney (hamstring) is inactive for the Falcons' receiving corps, so Casey Washington, KhaDarel Hodge, and Jamal Agnew could see bigger roles in the passing game behind Drake London. Both London and tight end Kyle Pitts Sr. should have slightly higher ceilings against Buffalo with Mooney out as well. McCloud has been a non-factor in fantasy in Atlanta in 2025, catching six of 14 targets for 64 yards and no touchdowns in four games played. His best game came in the season opener, when he had three catches for 51 yards in the loss to the Tampa Bay Buccaneers.

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Chicago Bears kicker Cairo Santos (thigh) has been ruled out for the Week 6 game on Monday night against the Washington Commanders. Santos drew a questionable tag on Saturday despite three full practices this week, and now he has been ruled out. The Bears elevated kicker Jake Moody from their practice squad to the active 53-man roster before the game, so he is in line to make his debut with Chicago on Monday Night Football. The 25-year-old Moody was cut by the San Francisco 49ers after going 1-for-3 in the season opener. Moody's struggles from last year continued in Week 1 in the Bay Area, but now he'll get another shot to prove himself with the Bears, with Santos injured. It could just be a one-week showcase, though, if Santos is ready to kick again for the team's Week 7 game against the New Orleans Saints.

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