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Jacksonville Jaguars wide receiver Dyami Brown (shoulder) exited during the second quarter of Sunday's Week 3 contest against the Houston Texans. He suffered the injury on a reception near the goal line and is officially questionable to return. At the time of his departure, he had caught two of three targets for seven yards through the air. Brown's absence should lead to more opportunities for Tim Patrick and Parker Washington behind Brian Thomas Jr. and Travis Hunter.

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Las Vegas Raiders tight end Michael Mayer (concussion) has been ruled out for the remainder of Sunday's Week 3 contest against the Washington Commanders. He exited near the end of the first quarter and was taken to the locker room to be evaluated for a concussion before being ruled out. The 24-year-old finishes this week with zero catches on one target. Ian Thomas will now take over as the Raiders' backup tight end behind superstar Brock Bowers.

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Cincinnati Bengals running back Samaje Perine (right thumb) has been ruled out for the remainder of Sunday's Week 3 contest against the Minnesota Vikings. He exited the contest late in the second quarter after fumbling the football. Cincinnati initially listed him as questionable before eventually downgrading him to out. He finishes Sunday's game with four carries, 21 rushing yards, four kick returns, 88 return yards, and the fumble. Tahj Brooks will operate as Chase Brown's backup until Perine is healthy again.

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Seattle Seahawks wide receiver Jaxon Smith-Njigba (illness) is officially active for his team's Week 3 matchup against the New Orleans Saints. Smith-Njigba was a late addition to the team's injury report heading into Sunday due to an illness, but it appears he'll still be able to suit up. Smith-Njigba has 17 catches for 227 yards on 23 targets through his first two games of 2025. He may see a slightly reduced snap share if he's still under the weather. Still, Smith-Njigba is a must-start fantasy wide receiver in Week 3.

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Seattle Seahawks running back Zach Charbonnet (foot) has officially been ruled out for his team's Week 3 matchup against the New Orleans Saints. Charbonnet is the team's leader in rush attempts (27) heading into Week 3. His absence should mean a significant increase in workload for Seattle running back Kenneth Walker III. Walker III has a touchdown and 125 rushing yards so far this season, 105 of which came in Week 2 against the Pittsburgh Steelers. With Charbonnet officially inactive, Walker III is a must-start fantasy running back in Week 3.

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Los Angeles Chargers rookie wide receiver Keandre Lambert-Smith is a healthy scratch for his team's Week 3 matchup with the Denver Broncos, per The Athletic's Daniel Popper. Lambert-Smith has not recorded an NFL catch and saw just one target across the Chargers' first two games of 2025. He's currently buried on the Chargers depth chart at wide receiver behind Ladd McConkey, Keenan Allen, Quentin Johnston, Derius Davis, and fellow rookie Tre' Harris. Lambert-Smith should remain off the radar of fantasy managers in redraft leagues.

From RotoBaller

Las Vegas Raiders tight end Michael Mayer (head) is being evaluated for a head injury and is questionable to return to his team's Week 2 matchup against the Washington Commanders. Mayer had one target in the game before getting injured. If he is unable to return, it could mean an increase in snaps for star Las Vegas tight end Brock Bowers. Third-string Raiders tight end Ian Thomas could also step into Mayer's role, particularly as an in-line blocker.

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Washington Commanders quarterback Jayden Daniels (knee) has a ligament sprain that prevented him from playing Sunday against the Las Vegas Raiders, according to FOX's Jay Glazer. The sophomore quarterback is able to move forward, but the injury has hampered his ability to move side-to-side, according to Glazer. In the meantime, Washington will start veteran backup Marcus Mariota while Daniels recovers.

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The San Francisco 49ers officially ruled out quarterback Brock Purdy (shoulder, toe) from playing in Week 3 against the Arizona Cardinals. The Iowa State product was initially feared to be out for upwards of a month, but made a late push to return earlier than expected. In any case, the 49ers will exercise caution and keep Purdy out for at least another week. Mac Jones will earn another start in his absence.

From RotoBaller

With wide receiver Jauan Jennings (ankle) injured, the San Francisco 49ers likely will turn to new addition Kendrick Bourne as a starter, coach Kyle Shanahan said. The 49ers also will be playing without tight end George Kittle (hamstring) and quarterback Brock Purdy (shoulder, toe) in the game, giving Bourne some streaming appeal for managers who are in a bind without Jennings. In most formats, however, managers should likely look elsewhere for a starting wide receiver.

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Cincinnati Bengals quarterback Joe Burrow (toe) has officially undergone surgery and is hopeful to make a return around mid-December, according to NFL Network's Ian Rapoport. For now, Cincinnati will turn to backup Jake Browning in Burrow's absence and hope to stay afloat in time to make a run at the NFL playoffs. Burrow's injury was a tough one for fantasy managers, who drafted the QB to be an every-week starter and didn't even get two full games. A return could happen within fantasy playoffs, but managers are going to have to lean on their bench or a trade in the meantime.

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Seattle Seahawks wide receiver Jaxon Smith-Njigba (illness) is expected to play Sunday against the New Orleans Saints, according to ESPN's Adam Schefter. The star receiver was added to the injury report due to the ailment and is listed as questionable, but Schefter reported that the team wanted to see how he felt, hence the late addition. Now that it seems like Smith-Njigba will play, fantasy managers can rest assured that a WR1 candidate can be locked into starting lineups.

From RotoBaller

Indianapolis Colts running back Tyler Goodson (elbow) will be active for the first time this season when his team visits the Titans in Week 3. Goodson is expected to compete with DJ Giddens for work behind Jonathan Taylor, although Taylor played 93% of the team's snaps in Week 2 and will stay the focal point of the offense. Goodson could work his way into a meaningful role as a deep-league flier or a handcuff to Taylor if he can pass up Giddens, who got some work in Week 1 in a lopsided win, but didn't get a touch in Week 2 against the Broncos. Keep an eye on how any work is divided between the backups, or if Taylor just features full-time.

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Cincinnati Bengals tight end Tanner Hudson will not play in Week 3 against the Vikings, after being listed as a healthy inactive. Hudson has yet to play an offensive snap for the Bengals this season although he was active each week. Instead of Hudson, tight end Cam Grandy will be active, and since he's more of a blocking specialist, that could mean the Bengals are planning to go more run-heavy if the game script allows against the Vikings. Hudson and Grandy are well off the fantasy football radar, but the switch in inactives could indicate a big workload is coming for Chase Brown.

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Cleveland Browns wide receiver DeAndre Carter (concussion) and kicker Andre Szmyt (calf) are both active and ready to go for Week 3's matchup against the Packers. Carter had to leave last week's game with a concussion, and Szmyt popped up on the injury report on Friday with a calf injury. He underwent an MRI, but everything looked good, so he's available as an emergency option at the position if needed. Carter has not played an offensive snap yet for the Browns, but he is an important special teams contributor, and he should be back in that role on Sunday after clearing the concussion protocol.

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Houston Texans wide receiver Braxton Berrios missed the first two games of the season with a hamstring injury but was able to return to practice this past week. He and Christian Kirk (hamstring) are ready to join the young Texans' receiving options behind Nico Collins, but Berrios won't make his Texans debut in Week 3, since he was listed as inactive. Rookie Jaylin Noel will continue to do work as a return specialist with Berrios inactive, while Kirk will work as the primary slot option with Collins, Xavier Hutchinson, and rookie Jayden Higgins all ahead of Berrios on the depth chart for now.

From RotoBaller

Tennessee Titans running back Kalel Mullings (ankle) and cornerback L'Jarius Sneed (back) are active in Week 3 against the Colts. Mullings was limited in practice this past week and listed as questionable. He originally injured his ankle in Week 1's loss to the Broncos and was inactive in Week 2 against the Colts. The rookie running back didn't get a touch in Week 1 and seems to be mainly a special teams contributor at this point in his career. Sneed missed practice this week with a back injury, but he'll be able to play as well, which is especially important since the team's second CB, Jarvis Brownlee Jr. (ankle), is not active, leaving a rotation at the corner spot opposite Sneed against the Colts. The Titans' banged-up corners could improve the matchup for Michael Pittman Jr. and Josh Downs as the Colts look to move to 3-0 on the season.

From RotoBaller

According to Tracy Wolfson of CBS, Minnesota Vikings quarterback J.J. McCarthy (ankle) is targeting a return in Week 7 following their week 6. Wolfson noted that McCarthy was not placed on IR and should be in the mix to return following their Week 6 bye. Managers should continue to monitor his status, as it appears the second-year QB is not expected to miss an extended period. While he remains sidelined, NFL journeyman Carson Wentz is slated to serve as Minnesota's QB1. During his first two games of his NFL career, McCarthy struggled to find much consistency as he went 24-for-41 with just 301 yards and a modest 2:3 TD:INT. However, since he missed his entire rookie season due to a meniscus tear, he may see some growing pains. Wentz carries QB2 value with upside in all formats for the time being, as he could find success throwing to Justin Jefferson and Jordan Addison when he returns from suspension next week.

From RotoBaller

Los Angeles Rams tight end Colby Parkinson (shoulder) is officially active for Sunday's contest against the Philadelphia Eagles. However, rookie tight end Terrance Ferguson is a healthy scratch. Parkinson carried a questionable tag following Friday's practice after logging three straight limited sessions. However, the 26-year-old was able to turn the corner. Parkinson was unable to play in Week 2 but operated as the team's No. 2 tight end in the season opener. In this contest, Parkinson caught both of his targets for -6 yards. This afternoon, managers should expect Parkinson to return to a reserve role as Tyler Higbee should see the majority of the snaps as the lead tight end.

From RotoBaller

Carolina Panthers wide receiver Xavier Legette (hamstring) is listed as inactive for Sunday's contest against the Atlanta Falcons. Legette was listed as a limited participant throughout the team's practices this week but was unable to progress enough to suit up. Managers should continue to monitor his status as the team prepares for their Week 4 contest against the New England Patriots. Through the first two games of the season, Legette has been given a lead role in the offense but has been unable to find much success. Legette has been targeted 15 times but has only been able to catch four of them for a mere eight yards. With Legette missing this contest, fantasy managers should expect rookie wideout Tetaiora McMillan and veteran wideout Hunter Renfrow to lead the offense.

From RotoBaller