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Tennessee Titans wide receiver Elic Ayomanor had a two-catch, 18-yard showing in the Week 5 meeting with the Arizona Cardinals. While that performance didn't sit well with fantasy managers, the rookie has played relatively well in an offense that's struggled throughout the 2025 campaign. In Ayomanor's first five games in the league, he's totaled 14 grabs (29 targets) for 169 yards. He also leads the team with two receiving touchdowns. With the Titans coming off their first win of the year, Tennessee will look to pick up another victory on Sunday against the Raiders. Without question, Las Vegas hasn't looked the best either, so Cam Ward and company have a chance to get something going on the offensive end. However, even with a favorable opportunity on the horizon, Ayomanor's lack of volume this season means he'll need to find the end zone, or fantasy managers will likely be extremely disappointed. With that in mind, the 22-year-old can be viewed as a desperation flex choice in 12-team leagues and up.

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Pittsburgh Steelers running back Kenneth Gainwell played incredibly well in Week 4 and will return from a bye to face the Cleveland Browns in Week 6. Though he should still be involved, the return of Jaylen Warren (knee) certainly puts a cap on Gainwell's upside. To make matters worse, Gainwell will need to overcome a Cleveland defense that has limited opposing backs to the third-fewest fantasy points per contest. Because he can contribute in the passing game, Gainwell isn't entirely touchdown-dependent, but it's difficult to expect another big performance. Fantasy managers should treat Gainwell as a low-end flex option that can be started in a pinch this week.

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Tennessee Titans wide receiver Tyler Lockett was once considered a top wideout in the National Football League. Unfortunately, it appears those days are well behind him. In his first five games as a Titan, he's caught only seven passes (16 targets) for 52 yards. While the veteran had his first touchdown of the year in Week 5 against the Cardinals, it wasn't as a pass-catcher. Instead, it came after a wild sequence of events that included a Cam Ward interception followed by a Dadrion Taylor-Demerson fumble. With the Titans coming off a win, their first of the 2025 campaign, the team will look for another victory on Sunday versus the Raiders. Like Tennessee, Las Vegas hasn't looked good throughout the season. With that in mind, despite the favorable matchup on tap, Lockett hasn't played well enough to be classified as a starting option in any fantasy format.

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Pittsburgh Steelers running back Jaylen Warren (knee) is set to return to action in Week 6 against the division-rival Cleveland Browns. Though Kenneth Gainwell impressed in Warren's absence, the latter is expected to reclaim RB1 duties immediately after practicing in full all week. Fantasy managers should keep expectations in check, however, as the Browns are allowing the fewest yards per carry and third-fewest fantasy points per game to opposing running backs. If Pittsburgh is forced to lean on the passing attack, Warren should remain involved as a key target for quarterback Aaron Rodgers, especially with Calvin Austin III (shoulder) sidelined. While this isn't the most appealing matchup, Warren still checks in as the RB26 in RotoBaller's half-PPR rankings and profiles as a high-end flex play in most formats.

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Kansas City Chiefs quarterback Patrick Mahomes will take on the Detroit Lions on Sunday night in Week 6. Mahomes completed 29 of 41 pass attempts (71%) for 318 yards and a touchdown in last week's loss to the Jacksonville Jaguars. Despite the loss, the Chiefs superstar set a new season-high for passing yards and completion percentage. Mahomes also rushed six times for 60 yards and a touchdown in Week 5. Kansas City's offense hasn't quite hit its stride, but Mahomes has still been valuable for fantasy. The 30-year-old has recorded at least 57 rushing yards and a rushing touchdown three times in five weeks, giving him a strong floor to go along with his passing production. Mahomes should continue being a valuable fantasy asset against the Lions, who have scored the most points in the league this season. The Sunday night matchup has the highest total of the week, meaning that Mahomes and the Chiefs will need to score a lot to keep up with Detroit. Mahomes is ranked QB4 in our RotoBaller rankings, making him a strong QB1 this week.

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Pittsburgh Steelers quarterback Aaron Rodgers is returning from a bye in Week 5 for an AFC North showdown against the Cleveland Browns on Sunday. Cleveland has been tough on opposing quarterbacks, holding the position to the sixth-fewest fantasy points per game. However, with the Browns even more dominant against the run, Pittsburgh may be forced to lean on Rodgers and the air attack despite Jaylen Warren's return. Though receiver Calvin Austin III (shoulder) has been ruled out, Rodgers could find success with his favorite target, DK Metcalf, after the two displayed strong chemistry in Week 4. Still, this contest is expected to be a low-scoring defensive battle, keeping Rodgers in the low-end QB2 range in superflex leagues.

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Dallas Cowboys quarterback Dak Prescott has been on another level lately. Over the last two games, Prescott has thrown for 556 yards with seven touchdowns and zero interceptions. He's missing his top wide receiver in CeeDee Lamb (ankle), but somehow is putting together fantastic numbers without him. Now, Prescott heads into a plus-matchup against the Carolina Panthers defense in Week 6. The 32-year-old has found a way to get it done without Lamb and he figures to do it again on Sunday. Fantasy managers should consider Prescott a top tier QB1 for this weekend

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Dallas Cowboys running back Javonte Williams has been one of the best backs in the league early in the season. The 25-year-old has found a new home in Dallas and appears to be earning himself a nice payday at the end of the season. Last week, Williams rushed 16 times for a season-high 135 yards with a touchdown in the win over the New York Jets. Williams has rushed for over 75 yards in four of the first five games this season. He remains an elite RB1 for the upcoming plus-matchup against the Carolina Panthers in Week 6.

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Tennessee Titans wide receiver Calvin Ridley finally was able to have success on the field during last week's game against the Arizona Cardinals. Ridley came into last week's game with three receptions for 57 yards over his last two games. The 30-year-old came out of nowhere and posted a huge performance in the win. Ridley hauled in five of his 10 targets for 131 yards, but was held out of the endzone. The hope is that Ridley and rookie quarterback Cam Ward continue building chemistry each week. Ridley has a plus matchup against the Las Vegas Raiders in Week 6. Fantasy managers should feel fine with plugging in Ridley as a WR3.

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Tennessee Titans running back Tony Pollard continues to be a solid contributor early in the season. Last week, Pollard rushed the ball 14 times for 67 yards and a touchdown in the win over the Arizona Cardinals. Pollard has rushed for 60 yards or more in four of his first five games of the season. The return of Tyjae Spears figures to slowly take away some of Pollard's value, but for now fantasy managers shouldn't be worried. Pollard has a plus matchup against the Las Vegas Raiders defense in Week 6. He should be able to offer low-end RB2 value for this weekend. Pollard continues succeeding, so the Titans are likely going to continue feeding him the ball.

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Las Vegas Raiders kicker Daniel Carlson remains a low-upside option for fantasy owners despite a potentially favorable Week 6 matchup against the Titans. The Raiders' offense has struggled to sustain drives, posting the league's second-highest turnover rate at 18.5%, and quarterback Geno Smith's inconsistency compounds Carlson's limited scoring opportunities. Even in games with red zone chances, the Raiders' inefficiency reduces Carlson's fantasy ceiling, making him a risky play. Until Las Vegas' offense becomes more consistent and turnover-prone plays are minimized, Carlson is unlikely to provide the reliable fantasy production owners hope for, and those with stronger options at the position should continue looking elsewhere for week-to-week stability.

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Tennessee Titans quarterback Cam Ward was able to have more success through the air during last week's game against the Arizona Cardinals. Ward completed 21-of-39 passing attempts for a career-high 265 passing yards with zero touchdowns and one interception in the win. The 23-year-old helped lead a fourth quarter comeback and finally started building chemistry with Calvin Ridley. Despite that, Ward hasn't done enough on the field to warrant starting even against the shaky Las Vegas Raiders defense in Week 6.

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San Francisco 49ers wide receiver Jauan Jennings (ankle) is currently listed as questionable ahead of the Week 6 matchup against the Tampa Bay Buccaneers. After missing last week's game, Jennings has been a limited participant in practice this week. It sounds like Jennings is trending towards being a game-time decision for Sunday's game. That's not exactly great news for fantasy managers with this game being a 4:25 pm ET kickoff this weekend. That means, fantasy managers will need to have another late afternoon option in case Jennings is unable to go. If active, Jennings should offer WR3 value with quarterback Mac Jones (oblique, knee) also questionable for this game.

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Miami Dolphins wide receiver Malik Washington had his busiest game of the season in Week 5 against the Panthers. He played about his normal amount of snaps but set a season-high with four catches on his five targets. He ended up with no yards on those four catches, but he did seem to get a little more work with Tyreek Hill (knee) unavailable for the first time this year. Washington has shown big-play ability in the return game, but he hasn't been able to get loose for any big receptions. He'll have a tough matchup this week against the Chargers, which is why he's only the WR57 in RotoBaller's rankings, but he does bring boom-or-bust potential if you need a deep league or DFS flier at receiver

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Las Vegas Raiders tight end Michael Mayer is on track to return in Week 6 after being a full participant in practice throughout the week. Mayer has not played since suffering a concussion on September 21 but is expected to reclaim the starting role with Brock Bowers (knee) still sidelined. While Mayer doesn't offer the same explosive playmaking ability as Bowers, his steady hands and blocking versatility should make him a reliable complementary option in the Raiders offense. Fantasy managers, however, should temper expectations--Mayer is projected as TE17 this week, placing him outside the starting range in standard leagues. Still, with Bowers' recovery timeline uncertain, Mayer could see expanded opportunities in the weeks ahead and is worth monitoring as a potential streamer or stash in deeper formats.

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Las Vegas Raiders rookie wide receiver Jack Bech is beginning to make his presence felt, turning in his most productive game of the season in Week 5. After playing just 10% of snaps in Week 4, Bech saw his snap share jump to 53% and drew five targets, finishing with a career-high 27 receiving yards. While those numbers don't yet warrant fantasy consideration in standard formats, the increased involvement is an encouraging sign for the rookie's development. If Bech continues to earn a steady role in the Raiders' offensive rotation, he could emerge as a deeper-league stash with intriguing dynasty upside. For now, Bech should remain on the fantasy radar as a potential riser in an offense still searching for consistent playmakers aside from Ashton Jeanty.

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Despite getting a questionable tag on the final Week 6 injury report on Friday, San Francisco 49ers quarterback Mac Jones (knee, oblique) is expected to play and make his second straight start against the Tampa Bay Buccaneers with Brock Purdy (toe) missing his fourth game of the year, according to ESPN's Nick Wagoner. Jones was limited in practice all week with left-knee and oblique injuries, but head coach Kyle Shanahan said on Thursday that the former Patriots QB is slated to start on Sunday. The 27-year-old's knee injury dates back to a preseason game before he aggravated it in Week 3. Jones strained his oblique on the final offensive snap in last Thursday's win over the Los Angeles Rams. He's clearly not 100% going into Week 6, making a repeat of his 300-yard performance in Week 5 unlikely, especially with receiver Ricky Pearsall (knee) out for a second straight game. Consider Jones a low-end QB2 this weekend.

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Miami Dolphins wide receiver Jaylen Waddle will have an opportunity to step up as the team's top receiver the rest of the season after Tyreek Hill (knee) was lost for the season in Week 4. In Week 5, Waddle delivered a big game, hauling in six of his nine targets for 110 yards and a touchdown against the Panthers. He set season highs in catches, targets, and yards, while scoring his third touchdown in the last four weeks. Waddle and the Dolphins will look to bounce back from last week's loss to Carolina, as they host the Chargers. The Chargers' defense has done a good job against receivers this season, but Deebo Samuel did light them up for eight catches, 96 yards, and a touchdown last week. Waddle should be primed for another high-volume game and is the WR17 in RotoBaller's Week 6 rankings.

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Las Vegas Raiders wide receiver Tre Tucker remains an intriguing name for fantasy managers, but continues to struggle with consistency heading into Week 6. The speedy wideout has shown flashes of big-play ability, yet his week-to-week production remains unpredictable, making him a tough player to trust in starting lineups. Tucker's boom-or-bust nature keeps him just outside of the flex range for most fantasy formats, though his increasing involvement in the Raiders' offense makes him a worthy stash candidate. As the team continues to search for reliable playmakers with Brock Bowers sidelined, Tucker's explosive potential gives him long-term appeal, but until he develops steadier usage and target volume, he's best viewed as a bench stash in all leagues rather than a dependable weekly starter.

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Las Vegas Raiders wide receiver Jakobi Meyers has seen his fantasy relevance fade in recent weeks and should be avoided in starting lineups heading into Week 6. Despite the Raiders frequently playing from behind, their passing game ranks just 15th through five weeks, with Meyers failing to separate himself from the pack. He saw an even target share with Tre Tucker and practice-squad call-up Albert Okwuegbunam in Week 5, signaling a troubling trend for the veteran wideout. The emergence of Tucker, combined with the Raiders' growing emphasis on the running game led by Ashton Jeanty, has further diminished Meyers' role. Until he reclaims consistent targets, Meyers should be treated as a low-end WR3 or bench option in standard formats heading into this week's matchup.

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