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San Francisco 49ers wide receiver Jauan Jennings (ankle) is currently listed as questionable ahead of the Week 6 matchup against the Tampa Bay Buccaneers. After missing last week's game, Jennings has been a limited participant in practice this week. It sounds like Jennings is trending towards being a game-time decision for Sunday's game. That's not exactly great news for fantasy managers with this game being a 4:25 pm ET kickoff this weekend. That means, fantasy managers will need to have another late afternoon option in case Jennings is unable to go. If active, Jennings should offer WR3 value with quarterback Mac Jones (oblique, knee) also questionable for this game.

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Miami Dolphins wide receiver Malik Washington had his busiest game of the season in Week 5 against the Panthers. He played about his normal amount of snaps but set a season-high with four catches on his five targets. He ended up with no yards on those four catches, but he did seem to get a little more work with Tyreek Hill (knee) unavailable for the first time this year. Washington has shown big-play ability in the return game, but he hasn't been able to get loose for any big receptions. He'll have a tough matchup this week against the Chargers, which is why he's only the WR57 in RotoBaller's rankings, but he does bring boom-or-bust potential if you need a deep league or DFS flier at receiver

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Las Vegas Raiders tight end Michael Mayer is on track to return in Week 6 after being a full participant in practice throughout the week. Mayer has not played since suffering a concussion on September 21 but is expected to reclaim the starting role with Brock Bowers (knee) still sidelined. While Mayer doesn't offer the same explosive playmaking ability as Bowers, his steady hands and blocking versatility should make him a reliable complementary option in the Raiders offense. Fantasy managers, however, should temper expectations--Mayer is projected as TE17 this week, placing him outside the starting range in standard leagues. Still, with Bowers' recovery timeline uncertain, Mayer could see expanded opportunities in the weeks ahead and is worth monitoring as a potential streamer or stash in deeper formats.

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Las Vegas Raiders rookie wide receiver Jack Bech is beginning to make his presence felt, turning in his most productive game of the season in Week 5. After playing just 10% of snaps in Week 4, Bech saw his snap share jump to 53% and drew five targets, finishing with a career-high 27 receiving yards. While those numbers don't yet warrant fantasy consideration in standard formats, the increased involvement is an encouraging sign for the rookie's development. If Bech continues to earn a steady role in the Raiders' offensive rotation, he could emerge as a deeper-league stash with intriguing dynasty upside. For now, Bech should remain on the fantasy radar as a potential riser in an offense still searching for consistent playmakers aside from Ashton Jeanty.

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Despite getting a questionable tag on the final Week 6 injury report on Friday, San Francisco 49ers quarterback Mac Jones (knee, oblique) is expected to play and make his second straight start against the Tampa Bay Buccaneers with Brock Purdy (toe) missing his fourth game of the year, according to ESPN's Nick Wagoner. Jones was limited in practice all week with left-knee and oblique injuries, but head coach Kyle Shanahan said on Thursday that the former Patriots QB is slated to start on Sunday. The 27-year-old's knee injury dates back to a preseason game before he aggravated it in Week 3. Jones strained his oblique on the final offensive snap in last Thursday's win over the Los Angeles Rams. He's clearly not 100% going into Week 6, making a repeat of his 300-yard performance in Week 5 unlikely, especially with receiver Ricky Pearsall (knee) out for a second straight game. Consider Jones a low-end QB2 this weekend.

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Miami Dolphins wide receiver Jaylen Waddle will have an opportunity to step up as the team's top receiver the rest of the season after Tyreek Hill (knee) was lost for the season in Week 4. In Week 5, Waddle delivered a big game, hauling in six of his nine targets for 110 yards and a touchdown against the Panthers. He set season highs in catches, targets, and yards, while scoring his third touchdown in the last four weeks. Waddle and the Dolphins will look to bounce back from last week's loss to Carolina, as they host the Chargers. The Chargers' defense has done a good job against receivers this season, but Deebo Samuel did light them up for eight catches, 96 yards, and a touchdown last week. Waddle should be primed for another high-volume game and is the WR17 in RotoBaller's Week 6 rankings.

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Las Vegas Raiders wide receiver Tre Tucker remains an intriguing name for fantasy managers, but continues to struggle with consistency heading into Week 6. The speedy wideout has shown flashes of big-play ability, yet his week-to-week production remains unpredictable, making him a tough player to trust in starting lineups. Tucker's boom-or-bust nature keeps him just outside of the flex range for most fantasy formats, though his increasing involvement in the Raiders' offense makes him a worthy stash candidate. As the team continues to search for reliable playmakers with Brock Bowers sidelined, Tucker's explosive potential gives him long-term appeal, but until he develops steadier usage and target volume, he's best viewed as a bench stash in all leagues rather than a dependable weekly starter.

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Las Vegas Raiders wide receiver Jakobi Meyers has seen his fantasy relevance fade in recent weeks and should be avoided in starting lineups heading into Week 6. Despite the Raiders frequently playing from behind, their passing game ranks just 15th through five weeks, with Meyers failing to separate himself from the pack. He saw an even target share with Tre Tucker and practice-squad call-up Albert Okwuegbunam in Week 5, signaling a troubling trend for the veteran wideout. The emergence of Tucker, combined with the Raiders' growing emphasis on the running game led by Ashton Jeanty, has further diminished Meyers' role. Until he reclaims consistent targets, Meyers should be treated as a low-end WR3 or bench option in standard formats heading into this week's matchup.

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Miami Dolphins running back Ollie Gordon II has played about 25% of snaps in four of his five games, usually logging about 15 snaps per game. He had a season-high nine carries in Week 3 against the Bills, when he scored his only touchdown of the year as well. The last two weeks, though, he hasn't been able to move into a larger role. Last week against the Panthers, he only managed -2 yards on three carries against the Panthers. The rookie does have some potential, but De'Von Achane is dominating the workload and production in the Dolphins' backfield for now. He will likely get some work against the Chargers in Week 6, but as the RB50 in RotoBaller's rankings, he's not a strong play in most leagues since his role has been so limited.

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Miami Dolphins running back De'Von Achane has been one of the best running backs all season, despite his team's offense running hot and cold. Achane hasn't run for 100 yards in any game, but he has supplemented with great production in the passing game. He has at least six catches in three of his last four games after hauling in six of his seven targets for 30 yards and a touchdown last week. He has four total touchdowns in five games while averaging 65.5 rushing yards and 34.6 passing yards per contest. This week, he and the Dolphins will take on the Chargers, who have been very good against the run this season, but did give up two running back touchdowns and 124 rushing yards against the Commanders. Achane's consistently high volume and big-play ability have kept him an elite RB1 in every matchup. In RotoBaller's Week 6 rankings, he is the No. 3 RB in PPR leagues and the No. 8 RB in standard leagues.

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Tampa Bay Buccaneers tight end Cade Otton finally was able to do some damage on the field last week. Otton hauled in four of his five targets for 81 yards during last week's win over the Seattle Seahawks. Before that, Otton was held to six receptions for 34 yards during the first four games. Recently, Bucs offensive coordinator Josh Grizzard said the team wants to get Otton more involved. The Bucs are going to be without wide receivers Mike Evans (hamstring) and Chris Godwin (leg) for Sunday's game against the San Francisco 49ers. That should mean that Otton sees more targets coming his way. All things are pointing to Otton getting more chances, so he should offer TE2 value in Week 6.

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Tampa Bay Buccaneers wide receiver Tez Johnson is expected to have an increased role during Sunday's game against the San Francisco 49ers. The Bucs will be without Mike Evans (hamstring) and Chris Godwin (leg) for Sunday's game. That being said, Johnson figures to move into the No. 3 receiver role for this Week 6 contest. Last week, Johnson hauled in four receptions for 59 yards in the win over the Seattle Seahawks. The rookie wideout has been quiet outside of that, but showed a promising performance in Week 5. The increased playing time could sneak Johnson onto the flex radar in deep leagues for this weekend.

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Tampa Bay Buccaneers wide receiver Sterling Shepard will move into the No. 2 role ahead of Sunday's matchup against the San Francisco 49ers. The Bucs will be without Mike Evans (hamstring) and Chris Godwin (leg) for Sunday's game. That means, Shepard will move up the depth chart this weekend. The 32-year-old has hauled in four receptions in three of the first five games. The problem has been the yardage as Shepard has 39 receiving yards or less in every game but one. There should be a handful of targets coming Shepard's way, but it's unclear what damage he'll do on the field. In most formats, Shepard should be viewed as a flex option for Week 6.

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Miami Dolphins quarterback Tua Tagovailoa will face the Chargers in a tough test at home during Week 6. Last week, Tua had one of his best games of the year, even though he was playing his first game without top receiver Tyreek Hill (knee). He completed 27-of-36 pass attempts for 256 passing yards and three touchdowns. He has thrown multiple touchdowns in four straight weeks and is up to 10 touchdowns on the year with just four interceptions. He's averaging just over 200 passing yards per game, while adding almost no rushing production. His recent success has been in favorable matchups, but this week, he'll face the Chargers, who have allowed the seventh-fewest fantasy points to the position. They have allowed just four passing scores all year and an average of only 188.2 passing yards per game. In the tough matchup, Tua is the No. 23 QB in RotoBaller's rankings, making him a borderline second QB but not a starter in most standard leagues.

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Tampa Bay Buccaneers running back Sean Tucker moved into the No. 2 role in the backfield during last week's game against the Seattle Seahawks. The assumption was that Tucker would see a handful of carries with Bucky Irving (foot) sidelined. Tucker didn't see much of the field as Rachaad White did most of the work on offense. Tucker rushed the ball three times for three yards while hauling in three passes for -4 yards in the win. The expectation is that Tucker will see a handful of touches this weekend, but isn't a trustworthy starter. Fantasy managers should keep Tucker on the bench for the Week 6 matchup against the San Francisco 49ers.

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Cincinnati Bengals star wide receiver Ja'Marr Chase (illness), who was listed as questionable for Week 6 on Sunday after missing Friday's practice due to an illness, is expected to play against the Green Bay Packers at Lambeau Field, sources told Matt Zenitz of CBS Sports. Chase was feeling a little under the weather on Friday, but he should be fine to play in a couple of days in what will be new quarterback Joe Flacco's starting debut in Cincinnati. The 25-year-old Chase has had three quiet games and two 100-yard games so far in 2025. A 6-110-2 line in last week's loss to the Detroit Lions proves why Chase is still a must-start in fantasy despite quarterback Joe Burrow (toe) potentially being out for the rest of the year. It remains to be seen what kind of chemistry Chase will have with Flacco, but the veteran signal-caller figures to target him heavily.

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Tampa Bay Buccaneers wide receiver Emeka Egbuka was unstoppable during last week's game against the Seattle Seahawks. Egbuka hauled in all seven of his targets for 163 yards and a touchdown in the win. The rookie wideout has now posted back-to-back games with at least 100 receiving yards. The Bucs are going to be without Mike Evans (hamstring) and Chris Godwin (leg) for Sunday's game against the San Francisco 49ers. That being said, Egbuka is expected to serve as the focal point in the receiving game. The 22-year-old has shown no signs of slowing down so he belongs as a strong WR1 for Week 6.

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Tampa Bay Buccaneers running back Rachaad White is set to make another start this Sunday versus the San Francisco 49ers. White made his first start of the season during last week's win over the Seattle Seahawks. The 26-year-old rushed 14 times for 41 yards with two touchdowns. He also hauled in four receptions for an additional 30 yards through the air. White figures to remain a focal point on offense with Bucky Irving (foot), Mike Evans (hamstring), and Chris Godwin (leg) all expected to miss Week 6. The Bucs really have no choice but to get White involved. He's a capable option in both the running and receiving game, which gives him borderline RB1 value for this weekend.

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Washington Commanders running back Jeremy McNichols worked mostly behind rookie Jacory Croskey-Merritt in Week 5, rushing just once for six yards and catching one of two targets for 12 yards. McNichols matched third-year running back Chris Rodriguez Jr. in snaps, each playing 13 snaps, while Croskey-Merritt led the way with 28. McNichols' role in pass protection is highly valued by the Washington coaching staff and will keep him involved in Washington's backfield committee. But his floor for touches is low, which limits his appeal in fantasy.

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Washington Commanders running back Jacory Croskey-Merritt broke out with his best game of the season in Week 5 against the Chargers, totaling 150 yards and two touchdowns on 16 touches. The Croskey-Merritt takeover finally happened in Week 5, posting a season-high 50.9% snap share, handling 50% of the team's rush attempts, and running 31.3% of the team's routes. All marks were the highest of any Washington back in Week 5, and he delivered with a remarkable performance. For the season, he's rushed 283 yards and four touchdowns on 43 carries, averaging a league-best 6.6 yards per carry. Offensive coordinator Kliff Kingsbury provided some reason to keep the optimism in check, saying that the rookie still has "ways to go" in terms of playing without the ball in his hands. His work in pass protection has improved, but that is still an area where veteran Jeremy McNichols is most trusted. Third-year back Chris Rodriguez Jr. saw his lowest snap count and fewest carries in a game since becoming active in Week 5, suggesting he may be slipping back into a depth role. Croskey-Merritt should be expected to handle the bulk of the touches again in Week 6 against a Bears defense that is allowing an absurd 6.1 yards per carry and the fourth-most PPR points per game to opposing running backs. He should be fired up as a high-upside RB2 on Monday night.

From RotoBaller