Atlanta Falcons quarterback Michael Penix Jr. is coming off two consecutive solid performances and will take on the 49ers on the road in San Francisco on Sunday night. The 49ers are middle of the pack in terms of fantasy points allowed to opposing QBs this year, and middle of the pack in terms of both passing (214.3) and rushing yards (107.3) on the season, however, San Francisco has allowed the fourth-most passing yards per game over the last three weeks (266.7). This is, of course, largely attributable to the absence of Nick Bosa (knee) and Fred Warner (ankle), who will both be out on Sunday as well (and for the rest of the season). While that bodes well for the Penix, the lefty QB could again be without Darnell Mooney (hamstring) who did not practice on Friday after getting in two limited sessions earlier in the week. All in all, the 25-year-old projects as a low-end QB2 on Sunday night with high-end QB2 upside with all the other offensive talent on this team at his disposal.

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With CeeDee Lamb set to return from a high-ankle sprain in Week 7 against Washington, Dallas Cowboys wide receiver Ryan Flournoy is expected to revert to a depth role in the Cowboys' receiving rotation. Flournoy played a meaningful role for Dallas in Lamb's absence, most notably in their Week 5 win over the Jets when he caught six of nine targets for 114 yards. Lamb will reassume his role as the top option in the Dallas passing game, with KaVontae Turpin also expected to return after a two-game absence due to a foot sprain. Flournoy's opportunities will likely be limited in Week 7 against Washington, and he is likely best left on waivers.

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Dallas Cowboys wide receiver George Pickens has held down the No. 1 WR role effectively with CeeDee Lamb (ankle) missing the last three games. Lamb is set to make his return in Week 7, sliding Pickens back into the No. 2 role. He racked up 19 catches for 359 yards and four touchdowns on 26 targets in Lamb's absence and should still have a big role in Dallas' elite offense. Even with Lamb back in the lineup, Pickens should be poised for another productive fantasy day against a vulnerable Washington secondary. He caught five of seven targets for 91 yards and a touchdown against them last year with the Steelers, and will rank as a borderline WR1 for Week 7.

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Dallas Cowboys wide receiver CeeDee Lamb will make his return in Week 7 against Washington after missing three games with a high-ankle sprain. Lamb practiced in full on Friday and was removed from the injury report ahead of Sunday. He's not expected to have any workload restrictions in his first game back and should reclaim his spot as the top target earner for QB Dak Prescott, who is playing as well as anyone in the league right now. It's a favorable matchup for Lamb against a gettable Washington secondary. Lamb will rank as one of the top WR options in fantasy for Week 7.

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Jacksonville Jaguars kicker Cam Little has a chance for a solid day in Week 7 against the Los Angeles Rams. In what should be a close matchup between two 4-2 teams, Little should have opportunities in what could be a tough game overall in London. The Jaguars' offense is good enough to move the ball well, while the Rams' defense is good enough to make plenty of defensive stops, which could mean a recipe for plenty of field goal opportunities. Little has been reliable from an accuracy and distance standpoint, so fantasy managers should feel fine starting Little in Week 7.

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Tampa Bay Buccaneers wide receiver Mike Evans' (hamstring) status for his team's Week 7 matchup against the Detroit Lions is "considered a pre-game decision," per ESPN's Adam Schefter. Schefter also notes that "there is more hope" for Evans than fellow Bucs wideout Emeka Egbuka (hamstring), who is also considered a game-time decision with a hamstring injury. Evans has missed the last three weeks for Tampa Bay after injuring his hamstring in Week 3. With Egbuka potentially sidelined and Chris Godwin (fibula) ruled out, Evans would likely dominate targets in Week 7 if he can make his return to the field. If he remains out, Buccaneers wideouts Sterling Shepard, Tez Johnson, and Kameron Johnson would all likely see an uptick in playing time and target share. Should Evans be available, he profiles as a high-end fantasy WR2 in Week 7 against Detroit.

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Tampa Bay Buccaneers wide receiver Chris Godwin (fibula) will miss his second straight game in Week 7 against the Detroit Lions due to a fibula injury. Godwin missed the first three weeks of the 2025 season while still recovering from a lower leg injury that ended his 2024 season. He recorded six catches for 52 yards on 14 targets across Weeks 5 and 6, but it appears he's still having lower-body issues that will keep him on the sidelines. Buccaneers wide receivers Mike Evans (hamstring) and Emeka Egbuka (hamstring) are both game-time decisions in Week 7, so Tampa Bay's wide receiver room is in flux. If one or both of Evans and Egbuka are out, the Buccaneers will likely rely on at least one of Sterling Shepard, Tez Johnson, and/or Kameron Johnson for wide receiver production against Detroit.

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New England Patriots tight end Hunter Henry has seen his fantasy production fluctuate on a week-by-week basis this year, ultimately ranking as the overall TE8 (PPR) through six contests. While his numbers have been enough to justify starting him in most weeks, managers may want to look elsewhere for production at the tight end position in Week 7. This week, Henry takes on the Tennessee Titans. Not only will the Patriots likely enjoy a positive game script -- leading to increased rush attempts and fewer pass attempts -- but the Titans have also been solid against the tight end position. Through Week 6, Tennessee has allowed the eighth-fewest fantasy points to tight ends. Henry's fantasy production this season has been largely based on game script and matchup, so with both of those factors not in his favor this week, the veteran is tough to trust. He ranks outside the top 12 fantasy tight ends ahead of Week 7 against the Titans.

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Tampa Bay Buccaneers wide receiver Emeka Egbuka (hamstring) suffered a hamstring injury in Week 6 that caused him to miss practice on both Thursday and Friday of this week. However, Egbuka was able to log a limited practice on Saturday, and his status for his team's Week 7 game against the Detroit Lions on Monday will be a "game-time decision," per Buccaneers head coach Todd Bowles. Egbuka has been excellent through the first six weeks of his NFL career, recording 27 catches for 469 yards and five touchdowns on 42 targets. Fantasy managers are now faced with a tough choice in Week 7, as they likely will not know whether Egbuka is active until Monday evening. The Buccaneers could get star wideout Mike Evans (hamstring) back from a hamstring injury against Detroit, but he remains a game-time decision as well. Tampa Bay will rely on Sterling Shephard, Tez Johnson, and Kameron Johnson for wide receiver production if Egbuka remains out.

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Atlanta Falcons wide receiver Drake London is coming off back-to-back 100-yard efforts, with a touchdown in both games as well. The 24-year-old is averaging over 10 targets and six catches per contest, with Week 7 bringing a matchup with the 49ers on Sunday night. The San Francisco defense has allowed the 18th-most half-point fantasy PPR points thus far, but has been much more susceptible to the pass in recent weeks with the losses of Nick Bosa (knee) and Fred Warner (ankle). Fellow wideout Darnell Mooney (hanstring) is questionable for this game, but if active, his presence should not diminish London's role, which is the unquestioned No. 1 receiver with a whopping 32.9 percent target share in 2025. The 6-foot-4 wide receiver's heavy usage on a weekly basis consistently puts him in the WR1 range, and he'll be a mid-range WR1 again versus the 49ers.

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New England Patriots wide receiver Kayshon Boutte was one of the top fantasy breakouts in Week 6, and he'll look to carry that momentum into another favorable matchup against the Tennessee Titans in Week 7. Boutte exploded last Sunday with five catches, 93 yards, and two touchdowns, taking advantage of a Saints defense that is notoriously poor against perimeter receivers. The Titans' run defense is far weaker than their pass defense, but Boutte still has an opportunity to excel with a positive game script in place. The Patriots could take several deep shots, looking to run up the score or take advantage of a defense that recently endured turmoil with the mid-season firing of head coach Brian Callahan. Boutte continues to be an intriguing WR3/flex with additional upside.

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Dallas Cowboys rookie running back Jaydon Blue has seen his first NFL game action over the last two weeks, but he's yet to play a significant role in the team's offense. Through two games, Blue has recorded seven rushing yards on seven carries and has not been targeted by Cowboys quarterback Dak Prescott. With veteran Cowboys back Miles Sanders (knee, ankle) on Injured Reserve, Blue figures to have an extended run as the team's RB2 behind Javonte Williams. Still, it would appear that the team does not currently trust Blue to do much beyond give Williams the occasional play off. That seems unlikely to change in a crucial divisional matchup in Week 7 against the Washington Commanders. Blue maintains long-term fantasy appeal as a handcuff, but he's not startable for fantasy managers in Week 7.

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New England Patriots wide receiver DeMario Douglas enjoyed plenty of success last Sunday against the New Orleans Saints, but he could come back down to earth in Week 7 against the Tennessee Titans. It was refreshing to see Douglas catch three passes for 71 yards and a touchdown last weekend, but in the five games prior to that, he was averaging just 1.4 catches, six yards, and 0.2 touchdowns per contest. If the start of the season is any indication, the slot receiver's breakout game last weekend is more of an anomaly than a sign of things to come. Right now, managers interested in the Patriots' receivers should have more faith in Stefon Diggs and Kayshon Boutte than Douglas. Heading into a matchup against the Titans, who have allowed the 15th-most fantasy points to wide receivers in 2025, Douglas is not a reliable fantasy option.

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Dallas Cowboys running back Javonte Williams had his worst game of the season in Week 6, recording just 34 scrimmage yards on 18 touches against the Carolina Panthers. Still, the 25-year-old is having an excellent season, as he's logged 559 yards from scrimmage and six touchdowns on 114 total touches through the first six weeks of 2025. The Cowboys have had a penchant for playing high-scoring games so far this season, and they could have another on tap in Week 7 against the Washington Commanders. Williams has played a workhorse, three-down role all year in Dallas, which put him in a good position to be productive each week. If there's any cause for concern, it's that Washington has allowed just four rushing touchdowns through its first six games. Still, Williams projects for close to 20 touches and profiles as a must-start fantasy running back in Week 7.

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New England Patriots running back Rhamondre Stevenson could see a large workload again in Week 7. The Patriots are facing off against the Tennessee Titans, which means the Patriots could enjoy a positive game script and therefore run the ball quite often. That would be good news for Stevenson, who has a slight edge on the lead-back role in New England despite some fumbling issues. Volume is just half the battle, though. Stevenson has struggled with efficiency at times this year, including last week when he had 13 carries for 18 yards (1.4 YPC). Fortunately for him, the Titans have been worn down by the run, allowing 4.7 YPC and the third-most fantasy points to running backs in 2025. With such a favorable matchup headed his way, Stevenson ranks as an RB3/flex.

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New England Patriots running back TreVeyon Henderson has continued to share backfield reps with Rhamondre Stevenson through six weeks of the 2025 season. As a result, the rookie has mostly stayed off the fantasy radar. That could change in Week 7 as Henderson has a prime opportunity to break out against the Tennessee Titans. New England is heavily favored over Tennessee, so a positive game script could lead to plenty of touches for the running backs, particularly Henderson. The Titans are pretty bad against the run, too, allowing the most rushing touchdowns and third-most fantasy points to opposing running backs in 2025. Between game script and matchup, Week 7 could offer the perfect storm for Henderson to separate himself from Rhamondre Stevenson and break out with a huge game. He's an intriguing RB3/flex with RB2 upside this week.

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Chicago Bears running back D'Andre Swift (groin) enters Week 7 listed as questionable, but he has expressed confidence that he'll suit up against the Saints. Swift is coming off a massive Week 6 performance, racking up 175 total yards and a touchdown on just 16 touches against a solid Commanders run defense. He handled 60% of the snaps, while rookie Kyle Monangai logged 31%, confirming Swift's hold on the lead role in Chicago's backfield. Facing a Saints defense that ranks 12th against running backs, Swift's volume will be crucial in this one. With the Bears favored for the second time this season and a run-heavy game script likely, Swift projects as a strong high-end RB2, assuming he's good to go against the Saints.

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Chicago Bears rookie running back Kyle Monangai posted a career-high in yardage in Week 6 coming out of the bye. Through five games, Monangai has totaled 129 scrimmage yards on 26 touches, operating as the clear backup to D'Andre Swift. Swift (groin) is questionable for Week 7 but has stated he expects to play, keeping Monangai in his reserve role. While the rookie could see a slight uptick in usage if Swift is limited, his fantasy value remains limited heading into the matchup with the Saints. Monangai should stay on fantasy benches in Week 7 as he continues to carve out a role in Ben Johnson's offense.

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Chicago Bears wide receiver Rome Odunze is coming off a quiet Week 6, recording just two catches for 32 yards. However, his day could have been much bigger, as Odunze had an 11-yard touchdown negated by a penalty and narrowly missed on a few deep connections with Caleb Williams. Despite the down week, the second-year receiver is still in the midst of a breakout season, totaling 328 yards and five touchdowns in five games, ranking as the WR7 on a per-game basis. Odunze draws a favorable matchup in Week 7 against the New Orleans Saints, who have allowed the eighth-most fantasy points to wide receivers this season. With the Saints' defense surrendering big performances to WR1s like Marvin Harrison Jr., Jauan Jennings, and Jaxon Smith-Njigba so far this season, Odunze is in a prime bounce-back spot. He should be viewed as a high-end WR2 this week, with significant big-play upside against a struggling Saints secondary.

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Chicago Bears wide receiver D.J. Moore (groin) is off the injury report and set to play in Week 7 against the New Orleans Saints. Moore was hospitalized following the team's Week 6 win over Washington due to a groin injury, but he practiced in full this week and is ready to go. It's been a slow start to the 2025 season for Moore, who has totaled 240 yards and one touchdown on 27 total attempts through five games. With Rome Odunze emerging as the team's WR1, Moore has struggled to find consistency. However, he gets a chance to rebound against a Saints defense that has allowed the eighth-most fantasy points to wide receivers this season. After New Orleans was torched by Drake Maye and the Patriots in Week 6, there's real upside for the Bears' passing attack this week. Moore profiles as a solid WR3 with bounce-back potential in Week 7.

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