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Los Angeles Rams wide receiver Puka Nacua has firmly established himself as a set-and-forget in fantasy football, which means that fantasy managers can confidently start him in all games without worrying about a potentially difficult matchup. Nacua has certainly shown that he can produce against any team, including the San Francisco 49ers, on whom he dropped 10 catches, 85 yards, and a touchdown last week. He remains the overall No. 1 receiver in fantasy football and is only trending upward as the season goes on. He's one of the steals of this year's fantasy drafts, as Nacua's production has league-winning potential even at his high ADP from the past summer.

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Los Angeles Rams wide receiver Davante Adams has continued to produce despite being second in the pecking order on his own team. The veteran receiver has 357 yards and three touchdowns this year, making him a high-end WR2 for week-by-week fantasy lineups. While Puka Nacua has earned the bulk of the attention in Los Angeles, Adams has made a significant impact, too, and his productivity so far should not be overlooked or taken for granted. The 32-year-old represents a safe, dependable WR2 or high-end flex option heading into Week 6 against the Baltimore Ravens.

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New England Patriots running back TreVeyon Henderson continues to make a push for more opportunities within the offense, but he hasn't seen much change in his fantasy value after five weeks of the NFL season. The Patriots continue to lean on Rhamondre Stevenson a little more than Henderson, even after the former lost three fumbles in three games. Stevenson touched the ball nine times on Sunday and was set up for two easy touchdowns despite averaging just two yards per carry. On the other hand, Henderson had eight touches and averaged four yards per carry, but still played less than half of the offensive snaps. He'll need to carve out a much larger snap share or start getting involved as a primary target for Drake Maye in the passing game before he becomes a worthwhile fantasy starter. In the meantime, he should be stashed on the bench.

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New England Patriots running back Rhamondre Stevenson continued to serve as the team's lead back despite losing a fumble on Sunday against the Buffalo Bills. He now has three lost fumbles in three games. Despite his ball security issues and inefficiency (he averaged 2.0 yards per carry in Week 5), Stevenson continues to see the field for more than half of the offensive snaps. New England's coaching staff has shown no interest in making a change to the backfield, with head coach Mike Vrabel even noting before Week 5 that they stuck with Drake Maye through some turnover adversity, and they're going to have Stevenson's back, too. We'd all like to see him get back to his 2022 form, but the fact of the matter is that rookie TreVeyon Henderson has looked better than Stevenson and therefore seems more deserving of the lead-back role. We could see a shift in dynamic by the end of the year, but for now, the Patriots are sticking with the 27-year-old.

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New England Patriots wide receiver Stefon Diggs made an enormous impression with his 10 catches and 146 yards on Sunday Night Football. The veteran receiver was able to get revenge on his old team, the Buffalo Bills, while turning in the best game yet with his new team. The 31-year-old has been everything the Patriots could have asked for (and more), making a variety of toe-drag plays and catches while being covered by a defender. He has 16 catches and 247 yards over his last two games, putting him firmly in the mid-range WR2 mix for Week 6 against the New Orleans Saints.

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Seattle Seahawks rookie quarterback Jalen Milroe entered the game in Week 5 against the Buccaneers for a speed option play, but he tossed it just a tad behind running back Kenneth Walker, leading to a fumble. It was an unfortunate result for the rookie from Alabama, as it wasn't the best play design, and it's not the easiest ask for him to come off the bench cold and be ready for the speed of NFL defenses. It was a costly fumble for Seattle, as they were driving in Tampa Bay territory and ultimately lost by a field goal. It's possible that this, combined with how well Sam Darnold has done, leads to fewer of these plays moving forward. Milroe is still a very good asset to own in dynasty, but he won't be an option in redraft, barring injury.

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San Francisco 49ers wide receiver Jordan Watkins (calf) was seen running on a side field at the team's first practice of the week on Monday. The rookie's NFL debut has been delayed, first by a preseason high ankle sprain and more recently by a calf injury. In Week 2, he was cleared to play but ended up as a healthy scratch. Since then, Watkins logged one limited practice in Week 3 but did not practice at all ahead of Weeks 4 and 5. A more thorough understanding of his status should come following the team's first official practice and injury report on Wednesday. San Francisco doesn't seem to be in a hurry to get their 2025 fourth-rounder into action, but with starters Ricky Pearsall (knee) and Jauan Jennings (ankle, ribs) both ailing, the team could use extra depth at wide receiver.

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New Orleans Saints rookie running back Devin Neal was inactive for the fourth straight game in Week 5 against the Giants. Neal suited up for the first time in Week 1 against the Cardinals and handled two carries for seven yards. In total, he played seven offensive snaps and four snaps on special teams. The rookie out of Kansas was able to earn two touches in his NFL debut, but has been a healthy scratch since. With the emergence of third-year back Kendre Miller and veteran Alvin Kamara holding things down, Neal has been relegated to a distant depth role.

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Tampa Bay Buccaneers rookie wide receiver Tez Johnson had his best game of his young career in Week 5 at Seattle, catching all four of his targets for 59 yards. Johnson nearly doubled his previous high in route participation, running a route on 53% of dropbacks in Week 5 after being at 27% the previous week in the first game Mike Evans missed. The rookie out of Oregon is very small at 5'10" and 154 pounds, but he is super shifty and quick in and out of his breaks. He looked the part out there in his first game with a significant snap share. He's a fairly specific type of player and won't ever run a full number of routes, but he is an intriguing waiver wire option in deeper leagues to consider in the short term while Evans is out.

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Los Angeles Rams rookie running back Jarquez Hunter has yet to play an offensive snap for the Rams this season, but has contributed on special teams in Weeks 3 and 4. However, with both starter Kyren Williams and No. 2 back Blake Corum losing fumbles in a Week 5 loss to the 49ers, there could potentially be an opportunity for Hunter to earn some touches on offense. The rookie out of Auburn has a great athletic and production profile and was raved about by head coach Sean McVay. Hunter is a good name to hold in dynasty leagues, but he has a tough path to relevancy in redraft leagues.

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San Francisco 49ers wide receiver Demarcus Robinson came out of last Thursday's 26-23 win over the Rams with just three receptions for 39 yards on seven targets. Despite the lackluster box score against his former team, Robinson led the team in routes run and air yards, and was second only to running back Christian McCaffrey in offensive snaps. The disappointing Week 5 performance will keep most managers away from burning FAAB dollars or waiver priorities on Robinson. However, if Ricky Pearsall (knee) and Jauan Jennings (ankle, ribs) are unavailable in Week 6, Robinson would be a sneaky late-week addition to fantasy football rosters and a dark horse flex candidate. Interested managers should monitor the situation in San Francisco closely throughout the week.

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Denver Broncos rookie wide receiver Pat Bryant played the third-most snaps among the team's receivers in Week 5 against the Eagles, trailing only Courtland Sutton and Troy Franklin. The rotation at wide receiver for Denver has been inconsistent week to week, outside of Sutton and Franklin. But Bryant has earned more snaps on offense for doing the dirty work as a blocker. The rookie got a lot of recognition for his block in the Bengals game that sprung Marvin Mims for a touchdown. Bryant got up a season high 54% of the routes in Week 5, jumping significantly from his high of 32% in the previous week. For the season, he's only caught two of four targets for 18 yards. It's still a very crowded Denver passing attack, and Bryant would need a lot to happen to be fantasy relevant in redraft leagues.

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New York Giants kicker Jude McAtamney is a risky option in Week 6, offering a low floor for the Thursday night matchup against the Eagles. In his two starts this season, the international kicker has scored nine fantasy points, making 2 of 2 field goals (long of 31 yards) and 3 of 3 extra points, but he failed to register a single field goal attempt in Week 5. The Giants' implied total for this game is one of the lowest of the week, and the Philadelphia defense ranks 30th in fantasy points allowed to kickers (11.4 FPTS/G), which suggests the Eagles are an ideal opponent to generate scoring opportunities. Despite his perfect 100% field goal percentage this season, the Giants' struggling offense will likely keep McAtameny's attempts down, making him a bench option until the offense proves capable of moving the ball reliably.

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New York Giants wide receiver Wan'Dale Robinson is a low-end WR3/Flex option for Week 6 against the Philadelphia Eagles, largely due to his volume in the short passing game. Ranked as the WR32 with an average of 8.88 fantasy points per game, Robinson's 78.3% snap percentage and team-high 22.7% target share (on 34 targets) point to a strong PPR floor, highlighted by his 23 receptions for 267 yards this season. However, the matchup is difficult as the Eagles have been a tough fantasy defense against wide receivers, ranking 16th and allowing an average of 21.4 fantasy points per game to the position. Furthermore, Philadelphia's red zone defense is elite, ranking 3rd with a 42.9% Defense Red Zone TD Rate, which will challenge Robinson's low-depth targets and his 3 end-zone targets. Given the Giants' implied team total of 17.25 points and rookie QB Jaxson Dart's third start, Robinson's upside is capped, making him a safer PPR option than a high-ceiling one.

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New York Giants tight end Daniel Bellinger is a desperation-level fantasy option for the Week 6 Thursday night tilt against the Philadelphia Eagles, despite seeing increased usage last week. Bellinger led the team in receiving yards in Week 5 with four receptions on four targets for 52 yards, earning 7.2 fantasy points while playing a 52% snap share, an elevated role due to the offense utilizing more two-tight end sets following the Malik Nabers injury. This short-term value is severely limited by a brutal matchup against the Eagles, who rank as the 4th toughest defense against tight ends, allowing an average of only 7.82 fantasy points against the position. Given the Eagles' 3rd-best red zone defense (42.9% Defense Red Zone TD Rate) and Bellinger's low ceiling (zero touchdowns in 2025), he remains off the fantasy radar for all but the deepest leagues.

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New York Giants tight end Theo Johnson is a risky, touchdown-dependent stream for the Thursday night matchup, despite his emergence as a key red-zone weapon. Johnson, the TE16 in fantasy with 7.08 fantasy points per game, has found the end zone three times this year, a figure made remarkable by the fact that rookie QB Jaxson Dart's only career touchdown passes have all gone to the tight end. This connection is vital, as Johnson operates with a high 75.4% snap share on his 15 receptions and 22 targets, but the Philadelphia Eagles present a brutal challenge. They rank as the 4th toughest fantasy defense against tight ends, allowing just 7.82 points against per game. Furthermore, the Eagles' elite 3rd-ranked red zone defense, which boasts a 42.9% Defense Red Zone TD Rate, significantly lowers the odds of Johnson continuing his unsustainable touchdown pace, making him a desperation play.

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Houston Texans rookie wide receiver Jaylin Noel had the best game of his young NFL career in Week 5 against the Baltimore Ravens, recording two catches for 13 yards and a touchdown on three targets. Noel has played a limited role so far this season, logging just five catches for 23 yards and a score on seven targets across five games. Noel has also yet to play more than 31% of the Texans' offensive snaps in any games and currently appears buried on the wide receiver depth chart behind Nico Collins, Xavier Hutchinson, Jayden Higgins, and Christian Kirk. The 23-year-old Noel has some long-term appeal and could be a stash candidate in deep redraft leagues. Still, in the short term, he's a long shot to provide consistent fantasy production.

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Through just five games in 2025, Dalton Kincaid has recorded 20 catches for 287 yards and a single-season career-high three touchdowns on 24 targets. While this could be the start of a long-awaited breakout season for the third-year tight end, there are a couple of worrying signs for fantasy managers to be aware of. For one, Kincaid has yet to play more than 55% of Buffalo's offensive snaps in any game this year as he splits playing time with Bills tight ends Dawson Knox and Jackson Hawes. Secondly, Kincaid is still averaging less than five targets per game, making him quite reliant on touchdowns for fantasy production. The 25-year-old has proven to have enough of a role in an excellent Bills offense that he profiles as a mid-to-low-end fantasy starter at the tight end position. Still, this may be a decent time to sell high on Kincaid.

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New York Giants running back Cam Skattebo is a volatile RB2 for the Week 6 Thursday night matchup against the Philadelphia Eagles, despite his recent workhorse usage. Skattebo, currently the RB17 in fantasy points per game (12.26 FPTS/G) on the season, has commanded a 66.7% timeshare in his last two games, recording 63 carries for 240 yards and two touchdowns, plus 18 receptions for 143 yards. The Eagles defense is a moderate run matchup, ranking 22nd by allowing 126.8 rushing yards per game and giving up four rushing touchdowns, yet they are a top-tier challenge near the goal line, boasting the 3rd best red-zone defense with a 42.9% touchdown rate. Furthermore, the Eagles have been generous to fantasy running backs, allowing 23.26 fantasy points per game (25th in the NFL), but the potential return of Tyrone Tracy Jr. and Skattebo's costly red-zone fumble last week temper expectations, making him a touchdown-dependent RB2/Flex play.

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Seattle Seahawks rookie wide receiver Tory Horton has flashed high-end potential through his first five NFL games, recording nine catches for 113 yards and three touchdowns on 14 targets. The 22-year-old has established himself as the clear WR3 in Seattle alongside star wideouts Jaxon Smith-Njigba and Cooper Kupp. Horton is tough to trust for fantasy managers in the short term because of his low target volume in a run-heavy Seahawks offense. Still, he's a name to monitor and a player for deep-league fantasy managers to stash for his long-term upside.

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