Cleveland Browns rookie running back Quinshon Judkins (leg) was carted off the field from his team's Week 16 matchup against the Buffalo Bills with an Aircast on his right leg. Ian Rapoport of NFL Network reports that Cleveland has ruled him out for the remainder of Week 16. While the exact nature of the injury is unclear, it appears to be a serious one for the 22-year-old. Judkins recorded eight carries for 22 yards and hauled in five receptions for 29 yards on six targets before exiting the game. The Browns entered the game already without running backs Dylan Sampson (hand, calf) and Jerome Ford (shoulder). Without their top three running backs, Cleveland will likely split backfield touches between Raheim Sanders and Trayveon Williams for the remainder of Week 16.

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Kansas City Chiefs quarterback Gardner Minshew (knee) is officially questionable to return to his team's Week 16 matchup against the Tennessee Titans due to a knee injury. Minshew completed three of eight pass attempts for 15 yards and recorded one carry for eight yards before exiting the game in the first half. Minshew was filling in for the injured Patrick Mahomes (knee), so Kansas City's quarterback depth is thinning rapidly. If Minshew is unable to return, Chris Oladokun would likely finish Week 16 under center for the Chiefs. A seventh-round pick out of South Dakota State in 2022, Oladokun has appeared in one career NFL game to this point. If Oladokun were to get injured, it's not clear who the Chiefs would turn to at quarterback.

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Dallas Cowboys wide receiver Ryan Flournoy (knee) is questionable to return to his team's Week 16 matchup against the Los Angeles Chargers due to a knee injury, per ESPN's Todd Archer. The 26-year-old got twisted up awkwardly after taking a big hit from Chargers linebacker Denzel Perryman. Before exiting the game, Flournoy recorded two receptions for 18 yards and a touchdown on two targets. Flournoy has emerged as the WR3 in Dallas alongside star wideouts CeeDee Lamb and George Pickens. If Flournoy is unable to return in Week 16, KaVontae Turpin and Jonathan Mingo could see more playing time at wide receiver, while tight end Jake Ferguson could see an uptick in targets.

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The Minnesota Vikings deemed running back Aaron Jones Sr. (ankle) questionable to return to Sunday's game at the New York Giants, but saw the veteran come back to action during the second quarter. Jones had to leave the opening drive, on which fellow running back Jordan Mason (ankle) also was injured. The Vikings weren't as lucky on Mason, who was quickly ruled out for the day. Now that the Vikings are down a running back, Zavier Scott will slide into the No. 2 role for the remainder of the game.

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The Minnesota Vikings ruled out running back Jordan Mason (ankle) from returning to Sunday's game against the New York Giants. Mason sustained the injury on the opening drive of the game and was carted back to the locker room after returning to the sideline. He'll finish the day with two carries for five yards. Luckily for Minnesota, it received good news on its other injured running back. Aaron Jones Sr. (ankle) also left the Vikings' first drive of the game, but was able to return later in the first half. Zavier Scott will back up Jones with Mason unable to play.

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The Minnesota Vikings classified running back Aaron Jones Sr. (ankle) as questionable to return to the Vikings' game against the New York Giants on Sunday. The Vikings saw both of their top two running backs sustain injuries on their first offensive series. Jones departed the game first, then Jordan Mason (ankle) took a shot, was carted to the locker room, and was also given a questionable tag. Jones was shown warming up again on the sideline, but if neither can return, Minnesota likely will lean on running back Zavier Scott and fullback C.J. Ham to handle the running game.

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Minnesota Vikings running back Jordan Mason (ankle) departed Sunday's game against the New York Giants after sustaining an injury on Minnesota's first offensive series. The first-year Viking lay on the turf for a few moments, walked gingerly to the sideline, and was eventually carted back to the team's locker room, where the team deemed him questionable to return. Even worse for the Vikings, Mason's injury occurred after top option Aaron Jones Sr. (ankle) had already sustained an injury of his own, left the game, and was given a questionable tag. If neither running back can return, that leaves Zavier Scott to handle most of the rushing work.

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Miami Dolphins quarterback Tua Tagovailoa was demoted to the third-string role ahead of Week 16, and NFL Network's Ian Rapoport reports that Tagovailoa has likely played his final snap with the team. Barring something unexpected, Miami will finish the year with Quinn Ewers and Zach Wilson as its active quarterbacks before re-evaluating the position group sans Tagovailoa during the offseason. Specifically, Rapoport said on Sunday that the Dolphins hope to trade Tagovailoa within the upcoming months. With that said, it may be tough to find a suitor who wants to take on the former first-round pick and the approximate $175 million cap hit that he carries over the next three years, especially after a tumultuous campaign in which he tallied 20 touchdowns and 15 interceptions.

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Tennessee Titans wide receiver Van Jefferson (back) is officially active for Sunday's game against the Kansas City Chiefs. Jefferson was questionable heading into Sunday. He missed Wednesday's practice before eventually being upgraded to a full participant on Friday. The 29-year-old has played a full-time role for the Titans since Week 6 but has not been overly productive, collecting 20 catches for 256 yards and a touchdown on 43 targets in that span. In a struggling Titans offense, Jefferson doesn't profile as a trustworthy fantasy option in Week 16. He is projected to continue to operate as the WR3 behind rookies Chimere Dike and Elic Ayomanor.

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Tennessee Titans rookie tight end Gunnar Helm (toe) is officially active for Sunday's game against the Kansas City Chiefs. Helm entered Sunday listed as questionable due to a toe injury. He was limited in practice on Wednesday and Thursday before logging a full practice on Friday. The rookie fourth-rounder has been a bright spot for the Titans this season, recording the most receptions among rookie tight ends in franchise history. Helm leads the team in catches and receiving yards over the last four games. During these four games, Helm has tallied 131 yards on 17 receptions and has found the back of the end zone once. He profiles as an upside TE2 in Week 16 for managers in deeper leagues.

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Houston Texans running back Woody Marks (ankle) is expected to be inactive for Sunday's Week 16 contest against the Las Vegas Raiders, according to NFL.com's Ian Rapoport. He had been listed as questionable and missed two of the Texans' three practices this past week. Although it was previously reported that Marks planned to play, the Texans are ultimately deciding to hold him out. Not only do they want to keep him fresh for the playoff push, but they can also feel comfortable about their chances with a slightly short-staffed backfield against a porous Las Vegas Raiders run defense that has allowed the second-most rushing touchdowns to running backs in 2025. Nick Chubb (ribs) should lead the way against Vegas, but we also expect to see a mix of Jawhar Jordan and Dare Ogunbowale, especially if the Texans jump out to an early lead.

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Miami Dolphins wide receiver Nick Westbrook-Ikhine will be a healthy inactive for Sunday's game against the Cincinnati Bengals. Westbrook-Ikhine has played in all 14 games for Miami so far this season, totalling 11 catches for 89 yards on 20 targets, but won't play in Week 16 due to a coach's decision. The 28-year-old wideout hasn't recorded a catch in four straight weeks and has only seen one target over this stretch. With Westbrook-Ikhine out, Malik Washington, Dee Eskridge, and Cedrick Wilson Jr. will be in the mix for more snaps and targets behind Jaylen Waddle in Week 16.

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New York Jets quarterback Justin Fields (knee) is officially inactive for Sunday's game against the New Orleans Saints, while Tyrod Taylor (groin, knee) will be active as the QB2 behind undrafted rookie Brady Cook. Both quarterbacks were questionable heading into Sunday, with Fields' status more in doubt after being limited in practice this week. As a result, the 2021 first-round pick will at least serve as the emergency QB3 in Week 16. Taylor was expected to serve as the backup to Cook after logging a full practice on Friday. Cook shouldn't be considered as a fantasy option against a New Orleans Saints defense that has been stingy against the pass in recent weeks. In his NFL debut last weekend, Cook threw three interceptions with just one passing score and 176 passing yards.

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Tampa Bay Buccaneers wide receiver Sterling Shepard (coach's decision) is a healthy scratch for Sunday's Week 16 contest against the Carolina Panthers. Shepard didn't log a snap in last week's loss to the Falcons, as he saw his role disappear with Mike Evans and Jalen McMillan returning from injured reserve. Now, with Tampa Bay carrying only five wide receivers into today's divisional battle with Carolina, Shepard is the odd man out, rather than fellow depth receiver Tez Johnson. Mike Evans, Chris Godwin, and Emeka Egbuka continue to lead this receiver room, while McMillan and Johnson fill depth roles. Shepard can be dropped in most fantasy leagues.

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Buffalo Bills wide receiver Mecole Hardman (calf) is officially active for Sunday's game against the Cleveland Browns. Hardman was activated off Injured Reserve on Saturday and will play in place of Keon Coleman, who will serve as a healthy inactive for the third time this season. Hardman was upgraded to a full participant in practice on Thursday and Friday after being limited on Wednesday. The former Kansas City Chiefs wideout landed on IR after injuring his calf in his first game with the Bills in Week 11's win over the Tampa Bay Buccaneers. Hardman is unlikely to play a major role in the Bills' spread-out passing attack and shouldn't be in any fantasy lineups in Week 16.

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Chicago Bears wide receiver D.J. Moore hauled in five of seven targets for 97 yards and a touchdown, while adding 12 rushing yards in the 22-16 overtime victory over the Green Bay Packers. After being held without a catch in the first half, Moore erupted, reeling in the game-winning 46-yard touchdown pass from quarterback Caleb Williams. With Rome Odunze (foot) and rookie Luther Burden III (ankle) inactive for Saturday's showdown, Moore was the top receiver, leading the team in nearly every statistical category and playing a season-high 95% of the snaps. With no update on whether either receiver will be back by their Week 17 matchup against the San Francisco 49ers, Moore could once again operate as the WR1 in this offense and be a must-start option if Odunze and Burden are ruled out once again.

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Dallas Cowboys wide receiver Jalen Tolbert (coach's decision) and running back Jaydon Blue (coach's decision) are both healthy scratches for Sunday's Week 16 contest against the Los Angeles Chargers. Tolbert is now headed for his third consecutive absence, and he hasn't logged a catch since Week 8. Ryan Flournoy, KaVontae Turpin, and Jonathan Mingo have offered more value in their depth roles behind CeeDee Lamb and George Pickens, leading to Tolbert being inactive. He can be dropped in all fantasy leagues. Meanwhile, Blue remains the odd man out from the Cowboys' backfield and is inactive for the seventh game in a row. Dallas' backfield will continue to feature just two running backs -- Javonte Williams and Malik Davis -- as well as fullback Hunter Luepke. Blue can be dropped in redraft leagues, but he remains an intriguing dynasty stash.

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Los Angeles Chargers wide receiver Quentin Johnston (groin) is officially active for Sunday's game against the Dallas Cowboys. Johnston was listed as questionable after being a limited participant in practice this week while managing a groin injury. The 24-year-old missed last week's game against the Kansas City Chiefs, but he should return to a full-time role in a favorable matchup against the Dallas Cowboys' 32nd-ranked pass defense. The TCU product has played 12 games this season, collecting 42 receptions for 533 yards and seven touchdowns on 71 targets. He projects as an upside WR4 for Week 16, facing a weak Dallas secondary.

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New York Giants wide receiver Jalin Hyatt (coach's decision) is a healthy scratch for Sunday's Week 16 contest against the Minnesota Vikings. The former third-round pick continues to be an afterthought in the Giants' offense, and this week, it will cost him his spot on the gameday roster. Hyatt played only 6% of the offensive snaps in Week 15, and he has caught just five of his 14 targets for 35 yards this season. His absence is likely a direct result of Gunner Olszewski (concussion) returning from his one-week absence. The 24-year-old can be left on waivers in fantasy football.

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The New York Giants have declared OT Jon Runyan Jr., QB Russell Wilson, WR Ryan Miller, WR Jalin Hyatt, S Demetrius Flannigan-Fowles, DL Caleb Murphy and DL Rakeem Nunez-Roches inactive for Week 16.

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